During the transition of various apps to be fit for 14.5 we very soon encountered a problem with the newly integrated TinyMCE editor which replaces the old CKEditor for richtext controls on Xpages.
To reproduce create a new XPage and paste this code:
<?xml version="1.0" encoding="UTF-8"?>
<xp:view xmlns:xp="http://www.ibm.com/xsp/core">
<xp:div id="refresh">
<xp:inputRichText id="inputRichText1"></xp:inputRichText>
</xp:div>
<xp:div id="refresh2">
<xp:inputRichText id="inputRichText2"></xp:inputRichText>
</xp:div>
<xp:div>
<xp:button
value="PR RTF"
id="button1">
<xp:eventHandler
event="onclick"
submit="true"
refreshMode="partial"
refreshId="inputRichText1">
</xp:eventHandler>
</xp:button>
</xp:div>
<xp:div>
<xp:button
value="PR DIV"
id="button2">
<xp:eventHandler
event="onclick"
submit="true"
refreshMode="partial"
refreshId="refresh">
</xp:eventHandler>
</xp:button>
</xp:div>
</xp:view>
You can see 2 buttons, one of them refreshes the 1st control directly (which works perfectly fine using the old CKE) and the 2nd refreshes the container around the control. With TinyMCE on a Domino 14.5 you will see that refreshing the control destroys it where the partial refresh of the container does the trick here.
A defect article for this observation can befound here: https://support.hcl-software.com/csm?id=kb_article&sysparm_article=KB0123705
You can also see the 2nd control being destroyed everytime the 1st editor is being refreshed.

This means the following:
Domino 14.5 with the new richtext control breaks all apps that use more than one richtext field on a page and use partial refresh - which I assume are quite common. You may also check and consider re-designing your page(s) if you were used to refresh the richtext field directly. You now have to modify the refresh to use a container around the control.
A case is currently being processed, there is no KB article yet.